Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Vitamin D Switches BAF Complexes to Protect ß Cells.

Wei, Zong; Yoshihara, Eiji; He, Nanhai; Hah, Nasun; Fan, Weiwei; Pinto, Antonio F M; Huddy, Timothy; Wang, Yuhao; Ross, Brittany; Estepa, Gabriela; Dai, Yang; Ding, Ning; Sherman, Mara H; Fang, Sungsoon; Zhao, Xuan; Liddle, Christopher; Atkins, Annette R; Yu, Ruth T; Downes, Michael; Evans, Ronald M.

Cell ; 173(5): 1135-1149.e15, 2018 05 17.

Artigo em Inglês | MEDLINE | ID: mdl-29754817

2.

Stellate Cells in Tissue Repair, Inflammation, and Cancer.

Sherman, Mara H.

Annu Rev Cell Dev Biol ; 34: 333-355, 2018 10 06.

Artigo em Inglês | MEDLINE | ID: mdl-30028641

3.

Vitamin D receptor-mediated stromal reprogramming suppresses pancreatitis and enhances pancreatic cancer therapy.

Sherman, Mara H; Yu, Ruth T; Engle, Dannielle D; Ding, Ning; Atkins, Annette R; Tiriac, Herve; Collisson, Eric A; Connor, Frances; Van Dyke, Terry; Kozlov, Serguei; Martin, Philip; Tseng, Tiffany W; Dawson, David W; Donahue, Timothy R; Masamune, Atsushi; Shimosegawa, Tooru; Apte, Minoti V; Wilson, Jeremy S; Ng, Beverly; Lau, Sue Lynn; Gunton, Jenny E; Wahl, Geoffrey M; Hunter, Tony; Drebin, Jeffrey A; O'Dwyer, Peter J; Liddle, Christopher; Tuveson, David A; Downes, Michael; Evans, Ronald M.

Cell ; 159(1): 80-93, 2014 Sep 25.

Artigo em Inglês | MEDLINE | ID: mdl-25259922

4.

A vitamin D receptor/SMAD genomic circuit gates hepatic fibrotic response.

Ding, Ning; Yu, Ruth T; Subramaniam, Nanthakumar; Sherman, Mara H; Wilson, Caroline; Rao, Renuka; Leblanc, Mathias; Coulter, Sally; He, Mingxiao; Scott, Christopher; Lau, Sue L; Atkins, Annette R; Barish, Grant D; Gunton, Jenny E; Liddle, Christopher; Downes, Michael; Evans, Ronald M.

Cell ; 153(3): 601-13, 2013 Apr 25.

Artigo em Inglês | MEDLINE | ID: mdl-23622244

5.

Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion.

Sousa, Cristovão M; Biancur, Douglas E; Wang, Xiaoxu; Halbrook, Christopher J; Sherman, Mara H; Zhang, Li; Kremer, Daniel; Hwang, Rosa F; Witkiewicz, Agnes K; Ying, Haoqiang; Asara, John M; Evans, Ronald M; Cantley, Lewis C; Lyssiotis, Costas A; Kimmelman, Alec C.

Nature ; 536(7617): 479-83, 2016 08 25.

Artigo em Inglês | MEDLINE | ID: mdl-27509858

6.

Stromal cues regulate the pancreatic cancer epigenome and metabolome.

Sherman, Mara H; Yu, Ruth T; Tseng, Tiffany W; Sousa, Cristovao M; Liu, Sihao; Truitt, Morgan L; He, Nanhai; Ding, Ning; Liddle, Christopher; Atkins, Annette R; Leblanc, Mathias; Collisson, Eric A; Asara, John M; Kimmelman, Alec C; Downes, Michael; Evans, Ronald M.

Proc Natl Acad Sci U S A ; 114(5): 1129-1134, 2017 01 31.

Artigo em Inglês | MEDLINE | ID: mdl-28096419

7.

AID-induced genotoxic stress promotes B cell differentiation in the germinal center via ATM and LKB1 signaling.

Sherman, Mara H; Kuraishy, Ali I; Deshpande, Chetan; Hong, Jason S; Cacalano, Nicholas A; Gatti, Richard A; Manis, John P; Damore, Michael A; Pellegrini, Matteo; Teitell, Michael A.

Mol Cell ; 39(6): 873-85, 2010 Sep 24.

Artigo em Inglês | MEDLINE | ID: mdl-20864035

8.

BRD4 is a novel therapeutic target for liver fibrosis.

Ding, Ning; Hah, Nasun; Yu, Ruth T; Sherman, Mara H; Benner, Chris; Leblanc, Mathias; He, Mingxiao; Liddle, Christopher; Downes, Michael; Evans, Ronald M.

Proc Natl Acad Sci U S A ; 112(51): 15713-8, 2015 Dec 22.

Artigo em Inglês | MEDLINE | ID: mdl-26644586

9.

Erratum: Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion.

Sousa, Cristovão M; Biancur, Douglas E; Wang, Xiaoxu; Halbrook, Christopher J; Sherman, Mara H; Zhang, Li; Kremer, Daniel; Hwang, Rosa F; Witkiewicz, Agnes K; Ying, Haoqiang; Asara, John M; Evans, Ronald M; Cantley, Lewis C; Lyssiotis, Costas A; Kimmelman, Alec C.

Nature ; 540(7631): 150, 2016 12 01.

Artigo em Inglês | MEDLINE | ID: mdl-27706144

10.

Autotaxin-lysolipid signaling suppresses a CCL11-eosinophil axis to promote pancreatic cancer progression.

Bhattacharyya, Sohinee; Oon, Chet; Diaz, Luis; Sandborg, Holly; Stempinski, Erin S; Saoi, Michelle; Morgan, Terry K; López, Claudia S; Cross, Justin R; Sherman, Mara H.

Nat Cancer ; 5(2): 283-298, 2024 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-38195933

11.

Tumor Microenvironment in Pancreatic Cancer Pathogenesis and Therapeutic Resistance.

Sherman, Mara H; Beatty, Gregory L.

Annu Rev Pathol ; 18: 123-148, 2023 01 24.

Artigo em Inglês | MEDLINE | ID: mdl-36130070

12.

The Role of Stroma in Cancer Metabolism.

Kimmelman, Alec C; Sherman, Mara H.

Cold Spring Harb Perspect Med ; 2023 Sep 11.

Artigo em Inglês | MEDLINE | ID: mdl-37696660

13.

Spotlight on GOT2 in Cancer Metabolism.

Kerk, Samuel A; Garcia-Bermudez, Javier; Birsoy, Kivanc; Sherman, Mara H; Shah, Yatrik M; Lyssiotis, Costas A.

Onco Targets Ther ; 16: 695-702, 2023.

Artigo em Inglês | MEDLINE | ID: mdl-37635751

14.

Supervised learning of high-confidence phenotypic subpopulations from single-cell data.

Ren, Tao; Chen, Canping; Danilov, Alexey V; Liu, Susan; Guan, Xiangnan; Du, Shunyi; Wu, Xiwei; Sherman, Mara H; Spellman, Paul T; Coussens, Lisa M; Adey, Andrew C; Mills, Gordon B; Wu, Ling-Yun; Xia, Zheng.

bioRxiv ; 2023 Mar 25.

Artigo em Inglês | MEDLINE | ID: mdl-36993424

15.

Single-cell RNA sequencing reveals the effects of chemotherapy on human pancreatic adenocarcinoma and its tumor microenvironment.

Werba, Gregor; Weissinger, Daniel; Kawaler, Emily A; Zhao, Ende; Kalfakakou, Despoina; Dhara, Surajit; Wang, Lidong; Lim, Heather B; Oh, Grace; Jing, Xiaohong; Beri, Nina; Khanna, Lauren; Gonda, Tamas; Oberstein, Paul; Hajdu, Cristina; Loomis, Cynthia; Heguy, Adriana; Sherman, Mara H; Lund, Amanda W; Welling, Theodore H; Dolgalev, Igor; Tsirigos, Aristotelis; Simeone, Diane M.

Nat Commun ; 14(1): 797, 2023 02 13.

Artigo em Inglês | MEDLINE | ID: mdl-36781852

16.

Epigenetic changes during disease progression in a murine model of human chronic lymphocytic leukemia.

Chen, Shih-Shih; Raval, Aparna; Johnson, Amy J; Hertlein, Erin; Liu, Te-Hui; Jin, Victor X; Sherman, Mara H; Liu, Shu-Jun; Dawson, David W; Williams, Katie E; Lanasa, Mark; Liyanarachchi, Sandya; Lin, Thomas S; Marcucci, Guido; Pekarsky, Yuri; Davuluri, Ramana; Croce, Carlo M; Guttridge, Denis C; Teitell, Michael A; Byrd, John C; Plass, Christoph.

Proc Natl Acad Sci U S A ; 106(32): 13433-8, 2009 Aug 11.

Artigo em Inglês | MEDLINE | ID: mdl-19666576

17.

Lung CAFs Show T Cells the Velvet Rope.

Sherman, Mara H.

Cancer Discov ; 12(11): 2501-2503, 2022 11 02.

Artigo em Inglês | MEDLINE | ID: mdl-36321307

18.

A Cancer Cell-Intrinsic GOT2-PPARÎ´ Axis Suppresses Antitumor Immunity.

Abrego, Jaime; Sanford-Crane, Hannah; Oon, Chet; Xiao, Xu; Betts, Courtney B; Sun, Duanchen; Nagarajan, Shanthi; Diaz, Luis; Sandborg, Holly; Bhattacharyya, Sohinee; Xia, Zheng; Coussens, Lisa M; Tontonoz, Peter; Sherman, Mara H.

Cancer Discov ; 12(10): 2414-2433, 2022 10 05.

Artigo em Inglês | MEDLINE | ID: mdl-35894778

19.

Mesenchymal Lineage Heterogeneity Underlies Nonredundant Functions of Pancreatic Cancer-Associated Fibroblasts.

Helms, Erin J; Berry, Mark W; Chaw, R Crystal; DuFort, Christopher C; Sun, Duanchen; Onate, M Kathrina; Oon, Chet; Bhattacharyya, Sohinee; Sanford-Crane, Hannah; Horton, Wesley; Finan, Jennifer M; Sattler, Ariana; Makar, Rosemary; Dawson, David W; Xia, Zheng; Hingorani, Sunil R; Sherman, Mara H.

Cancer Discov ; 12(2): 484-501, 2022 02.

Artigo em Inglês | MEDLINE | ID: mdl-34548310

20.

A Presynaptic Protein Is a Net Gain for Pancreatic Tumor Progression.

Sherman, Mara H.

Cancer Discov ; 11(2): 230-232, 2021 02.

Artigo em Inglês | MEDLINE | ID: mdl-33531426

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Vitamin D Switches BAF Complexes to Protect ß Cells.

Stellate Cells in Tissue Repair, Inflammation, and Cancer.

Vitamin D receptor-mediated stromal reprogramming suppresses pancreatitis and enhances pancreatic cancer therapy.

A vitamin D receptor/SMAD genomic circuit gates hepatic fibrotic response.

Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion.

Stromal cues regulate the pancreatic cancer epigenome and metabolome.

AID-induced genotoxic stress promotes B cell differentiation in the germinal center via ATM and LKB1 signaling.

BRD4 is a novel therapeutic target for liver fibrosis.

Erratum: Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion.

Autotaxin-lysolipid signaling suppresses a CCL11-eosinophil axis to promote pancreatic cancer progression.

Tumor Microenvironment in Pancreatic Cancer Pathogenesis and Therapeutic Resistance.

The Role of Stroma in Cancer Metabolism.

Spotlight on GOT2 in Cancer Metabolism.

Supervised learning of high-confidence phenotypic subpopulations from single-cell data.

Single-cell RNA sequencing reveals the effects of chemotherapy on human pancreatic adenocarcinoma and its tumor microenvironment.

Epigenetic changes during disease progression in a murine model of human chronic lymphocytic leukemia.

Lung CAFs Show T Cells the Velvet Rope.

A Cancer Cell-Intrinsic GOT2-PPARÎ´ Axis Suppresses Antitumor Immunity.

Mesenchymal Lineage Heterogeneity Underlies Nonredundant Functions of Pancreatic Cancer-Associated Fibroblasts.

A Presynaptic Protein Is a Net Gain for Pancreatic Tumor Progression.